描述
Identification
C12H17ClN4OS·HCl·xH2O
M = 337,27 g/mol
CAS [67-03-8]
EC number: 200-641-8
Taric code: 2936 22 00
Synonyms
Thiamine hydrochloride, Aneurine hydrochloride
Applications
in the pharmaceutics industry, vitamin, in food industry, in pharma industry.
Specifications
assay (titr. with HClO4, referred
on dried sample)……………………………………….. 98,0 – 101,0 %
assay (HPLC, referred to
dried sample)……………………………………………. 98,0 – 102,0 %
identification…………………………………………… passes test
pH (2,5 %, H2O)……………………………….. 2,7 – 3,3
pH (1 %, H2O)…………………………………… 2,7 – 3,4
absorbance of an aqueous solution
(10 %) in a 1 cm cell at 400 nm…………………… max. 0,025 AU
nitrates (NO3)……………………………………. passes test
sulfates (SO4)……………………………………. max. 300 ppm
related substances……………………………………. passes test
residue on ignition……………………………………….. max. 0,1 %
water content……………………………………………… max. 5,0 %
Elemental impurities are analysed
according to guideline
CHMP/ICH/353369/2013.
Residual solvents are analysed
according to guideline
CPMP/ICH/283/95.
Physical data
• Bulk density: ~ 500 kg/m3
• Solub. in water: (20 ºC): soluble
• Melting point: ~ 248 ºC
• pH(25 g/l H2O, 20 ºC) ~ 2,7 – 3,3
Toxicological data
• LD 50 (oral, rat): 3710 mg/kg
• WGK: 1
• Poison class CH (Swiss): F
Transport/storage
• Store between 15ºC and 25ºC
商品評價
目前沒有評價。