芹菜素 4′,5,7-Trihydroxyflavone, 97% -25mg|ALFA

名  稱:4′,5,7-Trihydroxyflavone, 97%

別  名:Apigenin

原廠編號:L15041

CAS    :520-36-5

 

貨號: AF-L15041-25MG 分類:

描述

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化學性質

化學式 :C15H10O5

分子量 :270.24

熔 點 :ca 315° dec.

Storage & Sensitivity :Keep Cold.

可溶性:

Soluble in dimethyl sulfoxide (27 mg/ml) or 1M potassium hydroxide (50mg/ml).

應用

4′,5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

注釋

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with and strong oxidizing agents.

参考文獻

Hirano T.; Oka K.; Akiba M. Antiproliferative effects of synthetic and naturally occurring flavonoids on tumor cells of the human breast carcinoma cell line, ZR-75-1. Research Communications in Chemical Pathology and Pharmacology. 1989, 64 (1), 69-78.

Sunanda Panda.; Anand Kar. Apigenin (4‘,5,7-trihydroxyflavone) regulates hyperglycaemia, thyroid dysfunction and lipid peroxidation in alloxan-induced diabetic mice. Journal of Pharmacy and Pharmacology. 2007, 59 (11), 1543-1548.

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